Tottenham Hotspur ended their 17-year trophy drought after they beat Manchester United 1-0 in the Europa League final at the San Mames Barria in Bilbao.
Real Madrid are determined not to be knocked off their perch at the summit of European football this season as they prepare to start their campaign against Eintracht Frankfurt in the UEFA Super Cup in Helsinki on Wednesday.
Barcelona's January signings shone as a 4-2 win at Napoli booked their place in the Europa League last 16, while Rangers held off a Borussia Dortmund fightback to progress after a 2-2 draw in Glasgow.
Joan Laporta claimed Barcelona are "back as big players" but Thursday will mark another checkpoint in the club's decline as they face Napoli in the knock-out stage of the Europa League.
Manchester United sealed a spot in the Europa League final with an 8-5 aggregate win over AS Roma despite a 3-2 loss in the second leg, while a 0-0 draw in London was enough to see Villareal progress to the final beating Arsenal 2-1 on aggregate.
Ole Gunnar Solskjaer is looking to end the season on a high after Manchester United set-up a Europa League semi-final against Roma.
Arsenal thrashed Slavia Prague 4-0 to seal a 5-1 aggregate win, while Manchester United beat Granada 2-0 to earn a 4-0 aggregate win as both English sides progressed to the last four of the Europa League.
Manchester United took control of their Uefa Europa League quarterfinal tie against Granada after a 2-0 first-leg victory, while Arsenal were pegged back by a late Slavia Prague equaliser at the Emirates.
Paul Pogba made a staring return from injury as he inspired Manchester United to a 1-0 win over AC Milan in their Uefa Europa League second leg encounter on Thursday evening which saw the Red Devils progress to the quarters with a 2-1 aggregate win.