Jurgen Klopp felt Liverpool were on the wrong end of two key decisions as they slipped to a 3-2 defeat at West Ham and missed out on a slice of history.
Manchester City triumphed in the derby at United, Chelsea and Liverpool both dropped points and two managers lost their jobs.
Jurgen Klopp was furious with the officials after West Ham punished three mistakes from Liverpool goalkeeper Alisson Becker and ended the Reds' 25-match unbeaten run with a 3-2 victory on Sunday.
Antonio Conte has promised to give Dele Alli the chance to resurrect his Tottenham Hotspur career.
Thomas Tuchel admitted Chelsea had only themselves to blame as the Premier League leaders were held to a surprise 1-1 draw by struggling Burnley on Saturday.
Pep Guardiola praised his team for silencing Old Trafford after his Manchester City side eased to a comfortable 2-0 derby win over Manchester United.
Manchester United manager Ole Gunnar Solskjaer said he does not feel as though he is on borrowed time despite a chastening 2-0 defeat by Manchester City on Saturday.
Matej Vydra pounced to stun sloppy Chelsea and scramble Burnley a 1-1 Premier League draw at Stamford Bridge.
Liverpool are on the verge of surpassing the record of the club’s great side of the 1980s but manager Jurgen Klopp insists his players do not want to be compared as they are creating their own history.
Phil Foden warned Manchester United he was ready for the derby after excelling yet again in Manchester City’s latest thrashing of Club Brugge.