Arsenal's exile from the Champions League looks set to stretch into a sixth season after losing 2-0 at Newcastle United on Monday.
Manchester City showed no signs of a Champions League hangover on a weekend that could prove decisive in the battle for the Premier League title as they stretched their lead at the top of the table to three points.
Manchester City took advantage of Liverpool's stumble in the Premier League title race with a 5-0 demolition of Newcastle on Sunday, while Arsenal and Everton also picked up massive wins. Catch up with all the highlights and reaction here.
Manchester City moved a step closer to retaining the Premier League title with a 5-0 demolition of Newcastle United at the Etihad Stadium on Sunday evening.
Eddie Nketiah boosted Arsenal's bid to finish in the Premier League's top four with a brace in their 2-1 win against Leeds as the Yorkshire club dropped into the relegation zone after Everton's 2-1 victory at Leicester on Sunday.
Catch up with highlights from the Premier League as Liverpool managed to keep the pressure on Manchester City following their 1-0 win over Newcastle United at St. James' Park on Saturday.
Manchester City and Liverpool must quickly turn their focus from Champions League glory to the battle for the Premier League title, with no room for error in tricky away trips on Saturday.
Gabriel Jesus scored four goals as Manchester City thrashed Watford 5-1 to open up a four-point lead in the Premier League title race, while Arsenal beat Manchester United 3-1 to take control of the race for fourth as Tottenham Hotspur were held to a 0-0 draw by Brentford.
Eddie Nketiah boosted Arsenal's bid for a top-four finish in the Premier League as the striker's double inspired a dramatic 4-2 win against Chelsea on Wednesday.
Tottenham powered into fourth place in the Premier League with a 5-1 rout of Newcastle, while West Ham's 2-1 victory pushed Everton deeper into relegation trouble on Sunday.