Chelsea scored four unanswered goals in the second half to earn a comfortable 4-0 win over Burnley at Turf Moor, while Philippe Coutinho was the pick of Aston Villa's performers as they overwhelmed Southampton 4-0 at Villa Park on Saturday.
Manchester United make the short trip to Premier League leaders Manchester City on Sunday buoyed by their recent record at the Etihad as Leeds begin a new era under Jesse Marsch.
Manchester City opened up a six-point lead over Liverpool at the top of the Premier League this weekend but Manchester United dropped more points in their push for a top-four place.
Christian Eriksen made an emotional return to football eight months after his cardiac arrest on Saturday as Manchester United dropped points in their push for a Premier League top-four place with a 0-0 draw against Watford.
Catch up with highlights from Wednesday's Premier League action as Liverpool crushed Leeds 6-0 to close the gap on Premier League leaders Manchester City to three points, while Tottenham Hotspur fell to a 1-0 defeat at Burnley.
Liverpool made lightweight of Leeds United after they cruised to a commanding 6-0 victory at Anfield, while Burnley clinched a crucial 1-0 win over Tottenham Hotspur at Turf Moor on Wednesday evening.
Ralf Rangnick said Manchester United's fightback from blowing another half-time lead to beat Leeds 4-2 was the "best possible response" his side could give to reports of dressing room unrest.
There may be a Premier League title race after all as a Harry Kane-inspired Tottenham ended Manchester City's unbeaten run stretching back to October, while Liverpool kept up their chase of the leaders by seeing off Norwich.
Super subs Fred and Anthony Elanga stepped off the bench to fire Manchester United to a 4-2 win over Leeds United in a classic at Elland Road.
Tottenham Hotspur face a daunting trip to Manchester City this weekend, desperate to arrest a losing streak that threatens to derail their season as Manchester United brace themselves for a hostile reception at Leeds.