Arsenal secured a 2-0 victory over Newcastle United at St James' Park to keep the pressure on Manchester City at the top of the Premier League table.
A howler by David De Gea condemned Manchester United to a 1-0 defeat against West Ham at the London Stadium leaving their top-four hopes at risk.
Chelsea ended their winless run in the Premier League after defeating Bournemouth 3-1 at the Vitality Stadium on Saturday.
Liverpool closed to within one point of fourth-placed Manchester United as Mohamed Salah's decisive goal was enough to secure the Reds' sixth consecutive win in the Premier League.
A brace by Ilkay Gundogan condemned Sam Allardyce to defeat in his first game in charge of Leeds as Manchester City held on to a secure 2-1 win to move four points clear at the top of the Premier League.
Brighton avenged their recent FA Cup defeat to Manchester United by claiming a late 1-0 win thanks to Alexis Mac Allister's dramatic stoppage-time penalty.
Liverpool kept the pressure on Newcastle United and Manchester United after they snatched a narrow 1-0 victory over Fulham at Anfield on Wednesday evening.
Erling Haaland set a new Premier League goal record to help Manchester City defeat West Ham United 3-0 to move back to the top of the table on Wednesday.
Leeds United have appointed Sam Allardyce as their new manager for the final four games after sacking Javi Gracia.
Arsenal returned to the top of the Premier League following their 3-1 win over Chelsea at the Emirates Stadium as Frank Lampard's side slumped to a sixth consecutive defeat.