Liverpool took control of their Uefa Champions League quarterfinal tie against Benfica with a 3-1 win in Portugal while Manchester City will take a slender 1-0 lead into their second-leg against Atletico Madrid after a 1-0 win at the Etihad.
Kaizer Chiefs missed the chance to go second on the DStv Premiership table after playing out to a goalless against TS Galaxy at the FNB Stadium on Tuesday evening.
Orlando Pirates will have to get past Tanzanian giants Simba SC in the quarterfinals of the Caf Confederation Cup after the draw was made on Tuesday afternoon.
Mamelodi Sundowns will face off against Angolan side Petro de Luanda, while Pitso Mosimane’s Al Ahly will do battle against Moroccan giants Raja Casablanca.
Diego Simeone conceded on Monday that Manchester City have "better" players than Atletico Madrid but said Chelsea's Champions League success last year shows his team can still reach the semi-finals.
Watch as Manchester City duo Pep Guardiola and Bernardo Silva preview their upcoming Champions League quarter-final first leg against Atletico Madrid at the Etihad Stadium on Tuesday evening.
Watch as Liverpool duo Jurgen Klopp and Virgil van Dijk speak to the media ahead of their Champions League quarter-final clash against Benfica in Lisbon on Tuesday evening.
Chelsea face Real Madrid on Wednesday reeling from their heaviest defeat of the season, but Thomas Tuchel's battle-hardened ability to keep his players focused should ensure the Champions League holders are ready for the latest test of their resilience.
Al Ahly coach Pitso Mosimane has urged former Kaizer Chiefs coach Gavin Hunt to come and test the waters in North Africa after making history in South Africa.
Kaizer Chiefs are reportedly undecided on whether they want to take up their extension option on Samir Nurkovic’s contract after missing a deadline to do this, throwing his future at Naturena into doubt.