Reeza Hendricks struck 157 off 135 balls as the Central Gauteng Lions beat the Northerns Titans by three wickets in Centurion on Wednesday.
The only Division One teams to have tasted victory in round one, the Central Gauteng Lions and the EP Warriors, will face off in round two of the 4-Day Series that gets under way on Friday.
The EP Warriors clinched a thrilling one-wicket victory over the Northerns Titans in Centurion on Monday.
South Western Districts and Western Province have progressed to the quarter-finals of the T20 Knock Out tournament.
The Lions claimed their second win of the T20 Knock Out after beating South Western Districts by four wickets at the Kimberley Oval on Sunday.
Zubayr Hamza scored his maiden T20 century as Western Province beat the Lions by two runs in a crackerjack opening fixture of the CSA Provincial T20 Knock Out at the Kimberley Oval on Friday.