South Africa Olympic team will be without experienced defender Eric Mathoho and striker Lebo Mothiba when they face Iraq in the crucial Group A match on Thursday.
The 26-year-old defender was ruled out due to an ankle injury, which he suffered in the last 10 minutes of their 1-0 defeat against Denmark.
Mothiba was withdrawn because of a potential case of chicken pox, according to Safa.net.
However, Abbubaker Mobara, who suffering from a hamstring strain against the Danish side will be available for selection against Iraq.
South Africa will take on Iraq in their final Group A clash at Corinthians Arena in Sao Paulo.
Kick-off has been set for 03:00.