Dillyn Leyds will start at flyhalf when the Stormers take on the Blues at Newlands on Friday.
With Robert du Preez and Jean-Luc du Plessis out injured, Leyds will shift from wing to pivot, while Brandon Thomson will provide flyhalf cover on the bench.
Among the backs, fit-again Seabelo Senatla takes his place on the left wing, while Damian de Allende is set to make his return from injury off the bench.
Up front, the Stormers will be boosted by the return of Springboks Eben Etzebeth, Pieter-Steph du Toit and Frans Malherbe, while in the only other change to the forward pack, Oli Kebble switches with Ali Vermaak at loosehead prop.
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